Read more about the article Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Abstract Genome-wide association studies (GWAS) have identified >250 loci for body mass index (BMI), implicating pathways related to neuronal biology. Most GWAS loci represent clusters of common, noncoding variants from…

Continue ReadingProtein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Read more about the article Paediatric departments need to improve residents’ training in adolescent medicine and health: a position paper of the European Academy of Paediatrics.
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Paediatric departments need to improve residents’ training in adolescent medicine and health: a position paper of the European Academy of Paediatrics.

Abstract In many European countries, paediatric junior staff has no formal training in adolescent medicine and is ill-equipped to deal with issues and health problems such as substance use, unprotected…

Continue ReadingPaediatric departments need to improve residents’ training in adolescent medicine and health: a position paper of the European Academy of Paediatrics.
Read more about the article The Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for Preventing Cardiovascular Diseases.
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The Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for Preventing Cardiovascular Diseases.

Abstract Apolipoprotein A5 (APOA5 or APO A-V) polymorphisms have long been reported to be associated with cardiovascular disease and plasma lipid levels. The present study was undertaken to investigate the…

Continue ReadingThe Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for Preventing Cardiovascular Diseases.
Read more about the article – a novel candidate breast cancer susceptibility locus on 6q14.1.
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– a novel candidate breast cancer susceptibility locus on 6q14.1.

Abstract Most non- breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on…

Continue Reading– a novel candidate breast cancer susceptibility locus on 6q14.1.
Read more about the article Omega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model.
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Omega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model.

Abstract The purpose of this study was to evaluate the neuroprotective effects of omega-3 polyunsaturated fatty acid (ω3-PUFA) supplementation, alone or in combination with timolol eye drops, in a mouse…

Continue ReadingOmega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model.
Read more about the article Ancestry inference of 96 population samples using microhaplotypes.
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Ancestry inference of 96 population samples using microhaplotypes.

Abstract Microhaplotypes have become a new type of forensic marker with a great ability to identify and deconvolute mixtures because massively parallel sequencing (MPS) allows the alleles (haplotypes) of the…

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Read more about the article Improving ancestry distinctions among Southwest Asian populations.
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Improving ancestry distinctions among Southwest Asian populations.

Abstract The Kidd Lab panel of 55 AISNPs can provide up to 10 statistically relevant biogeographic groupings of a global set of populations. A second-tier panel would be useful for…

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Read more about the article Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.
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Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.

Abstract Epidemiological, biological, and molecular data suggest links between endometriosis and endometrial cancer, with recent epidemiological studies providing evidence for an association between a previous diagnosis of endometriosis and risk…

Continue ReadingGenetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.
Read more about the article Filling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective.
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Filling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective.

Abstract Cancer is believed to arise through the perturbation of pathways and the order of pathway perturbation events can enhance understanding and evaluation of carcinogenicity. This order has not been…

Continue ReadingFilling the gap between chemical carcinogenesis and the hallmarks of cancer: A temporal perspective.
Read more about the article Restless legs syndrome in Multiple Sclerosis patients: a contributing factor for fatigue, impaired functional capacity, and diminished health-related quality of life.
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Restless legs syndrome in Multiple Sclerosis patients: a contributing factor for fatigue, impaired functional capacity, and diminished health-related quality of life.

Abstract Objectives Restless legs syndrome (RLS) symptoms are common in Multiple Sclerosis (MS) patients. The aim of the current study was to examine for the first time whether RLS could…

Continue ReadingRestless legs syndrome in Multiple Sclerosis patients: a contributing factor for fatigue, impaired functional capacity, and diminished health-related quality of life.